In An additional study only one 100-mg/ kg dose of codeine administered to Expecting mice reportedly resulted in delayed ossification while in the offspring. There isn't any reports in people, and the importance of those conclusions to human beings, if any, isn't identified.
Promethazine shouldn't be utilized by kids young than 2 a long time as it might result in really serious (potentially deadly) gradual/shallow breathing. This issue has happened Despite having normal doses In this particular age group.
Drug interactions may perhaps change how your prescription drugs perform or boost your threat for critical Unintended effects. This document isn't going to include all possible drug interactions.
As a result of opportunity for fatal respiratory melancholy, usually do not administer promethazine and codeine concurrently to small children Tier
This medication may make you far more sensitive into the sun. Restrict your time and efforts in the sun. Prevent tanning booths and sunlamps. Use sunscreen and put on protecting apparel when outdoors. Notify your health practitioner immediately if you receive sunburned or have pores and skin blisters/redness.
Stimulation might be evident, especially in youngsters and geriatric clients. Convulsions may possibly hardly ever take place. A paradoxical-style response has long been reported in children receiving single doses of seventy five mg to 125 mg orally, characterized by hyperexcitability and nightmares.
Codeine: Narcotic analgesics, like codeine, exert their Most important consequences to the central anxious program and gastrointestinal tract. The analgesic consequences of codeine are on account of its central motion; nonetheless, the specific web pages of motion haven't been determined, and the mechanisms concerned seem like really complex. Codeine resembles morphine both of those structurally and pharmacologically, but its actions with the doses of codeine utilized therapeutically are milder, with significantly less sedation, respiratory melancholy, and gastrointestinal, urinary, and pupillary outcomes.
Patients should be encouraged to measure Promethazine with Codeine Oral Option having an precise measuring system. A house teaspoon is not an precise measuring machine and could lead to overdosage, especially when a half a teaspoon is measured. A pharmacist can advise an correct measuring product and can provide Recommendations for measuring the right dose. Promethazine and codeine may well bring about marked drowsiness or might impair the psychological and/or Actual physical talents demanded to the overall performance of probably dangerous responsibilities, for instance driving a automobile or running equipment.
The mixture of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric individuals lower than 6 many years of age, because The mixture may perhaps bring about fatal respiratory depression In this particular age inhabitants. It is necessary that promethazine hydrochloride and codeine phosphate syrup is measured with the precise measuring product (see Safeguards-Info for People).
The amount of drugs that you choose will depend on the strength with the drugs. Also, the number of doses you are taking every day, some time permitted among doses, along with the amount of time you take the medicine depend upon the professional medical trouble for which you are utilizing the medicine.
A Distinctive MedGuide Promethazine codeine syrup will likely be given for you with the pharmacist with each prescription and refill. Make sure you look at this details meticulously every time.
Most MAO inhibitors should also not be taken for two weeks in advance of treatment with this medication. Inquire your doctor when to start or prevent taking this medication.
Ahead of getting this medication, convey to your doctor or pharmacist In case you are allergic to any of its ingredients; or to opioid soreness relievers (for instance morphine); or For those who have some other allergies.
Study the Medication Guide supplied by your pharmacist Before you begin having promethazine/phenylephrine/codeine and each time you receive a refill. When you've got any issues, question your medical doctor or pharmacist.